Tuesday, August 9, 2011

Genzyme closes drug plant due to virus - Jacksonville Business Journal:

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Investors turned on the company’s stoci shortly after the news wasconfirmed Tuesday, pushing Genzyme’s (Nasdaq: stock down roughly 7 percent to $51.80 a Genzyme is currently working to sanitizee the facility and is collaborating with regulatory agencies as it workzs to resume production. But the companh does not expect the plant to be fully operational untill the endof July. The viruw is called Vesivirus 2117, and company officials say it has not been shownm to causehuman However, the virus is known to interferse with the growth of cells used to producd biologic drugs. Genzyme says the viruas was likely introduced througg a nutrient used in themanufacturing process.
Genzymwe has now confirmed that this viruds was the cause of decline in cell productivity attwo facilities, including the company’s Allston in two previous instances in 2008, which were subsequentlt fully addressed. Genzyme has previousl said that it is currently not making enough of the drugs Cerezymefor Gaucher’s disease and Fabrazymr for Fabry disease, to meet projected global The company is unsured how the virus will affect the Cerezyms production but expects Fabrazyme supply constraints to occur for a limitexd period beginning in September.
The companyu said it will workwith physicians, patiente and regulators to minimize the impact of this “The patients who need these therapies are our said Henri A. Termeer, Genzyme’sx chairman and chief executive “We are confident in the quality of the product produced in Allston and in our ability to resolve the issue affecting the The impact willbe temporary.” Genzymwe identified the virus at the Allstonn plant over the weekend and held a conference call with the

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